Matthias Mann


Prof. Dr. rer. nat. Dr. Dr. h.c.

Position Title

Director; Department of Proteomics and Signal Transduction
Max-Planck-Institute of Biochemistry



Contact Details

Max-Plnack-Institute of Biochemistry
Am Klopferspitz 18
82152 Martinsried (near Munich, Germany)


+49 89 8578 2557


+49 89 8578 2219






•  Georg August Universität Göttingen; B.A.; 1982; Physics, Mathematics 
•  Georg August Universität Göttingen; Master’s Degree; 1984; Physics 
•  Yale University; Ph.D.; 1988; Chemical Engineering

Professional Experience 

1989–1992  Post doctoral fellow and later Senior Scientist in the Department of Molecular 
Biology, University of Southern Denmark, Denmark 
1992-1998  Group leader of the Protein & Peptide Group, European Molecular Biology 
Laboratory (EMBL), Heidelberg 
1998-2007  Professor of Bioinformatics, Department of Biochemistry and Molecular Biology, 
University of Southern Denmark; Director of the Center for Experimental 
BioInformatics (CEBI) 
2005 -   Director at the Max-Planck Institute of Biochemistry, Martinsried, Germany 
2007 -  Additional appointment as director of the Department of Proteomics, The Novo 
Nordisk Foundation Center for Protein Research, Faculty of Heath Sciences, 
University of Copenhagen, Denmark


•  1991  Malcom Award by the journal Organic Mass Spectrometry 
•  1996  Mattauch Herzog Prize in Mass Spectrometry 
•  1997  Hewlett-Packard Prize for Strategic Research in Automation of Sample Preparation 
•  1998  Edman Prize by the “Methods in Protein Structure Analysis” Society 
•  1999  Bieman Medal for Outstanding Achievement in Mass Spectrometry (American 
Society for Mass Spectrometry) 
•  1999  Named second most cited scientist in chemistry in the years 1994 to 1996 by the 
Institute of Scientific Information 
•  1999  Elected visiting professor Harvard Medical School 2/3 
•  1999  Elected to the European Molecular Biology Organization (EMBO) 
•  2001  Bernhard and Matha Rasmussen’s Memorial award in Cancer Research 
•  2001  Meyenburg Cancer Research Award  
•  2001  Fesenius Prize for Analytical Chemistry by the German Chemical Society 
•  2004  Honorary Doctorate University Utrecht, Netherlands 
•  2004  Lundbeck Nordic Research Prize 
•  2004  Novo-Nordisk Prize (shared with Prof. Peter Roepstorff) 
•  2005  Anfinsen Award of the Protein Society 
•  2006  Biochemical Analysis Prize by the German Society for Clinical Chemistry and 
Laboratory Medicine 
•  2007  Honorary Professor at The Novo Nordisk Foundation Center for Protein Research, 
Faculty of Health Sciences, University of Copenhagen 
•  2007  2nd most cited European Scientist for the last ten years according to ScienceWatch 
•  2008  HUPO Distinguished Achievement Award in Proteomic Sciences (Shared with Prof. 
Denis Hochstrasser) 
•  2010  Friedrich Wilhelm Joseph von Schelling Prize awarded by the Bavarian Academy of 
•  2011  Fyodor Lynen Lecture Medal 2011 (German Society of Biochemistry and Molecular 
•  2012  Leibniz Prize of the German Research Society 
•  2012  Ernst Schering Prize 
•  2012  Louis-Jeantet Foundation Prize for Medicine 
•  2012  Körber European Science Award 
•  2013  Elected member of Leopoldina German National Academy of Sciences 
•  2013  Winner of m4 Award – Ministry of Economic Affairs supports Personalized Medicine 

Recent Editorial Board Memberships

•  Journal of Proteome Research 
•  Molecular and Cellular Proteomics 
•  Cell 
•  Carcinogenesis


Matthias Mann is currently involved in more than 13 external grants. Main sources: European 
Union, BMBF (The German Federal Ministry of Education and Research), State of Bavaria 
Ministry of Industry, Michael J Fox Foundation, Excellence Initiative of the Federal Republic of 
Germany and the German Research Foundation (DFG) as well as joint projects with various 
industrial concerns.


Dr. Mann has authored and co-authored more than 584 publications with more than 100,000 
citations according to ISI (h-factor more than 150), making him one of the most highly cited 
researchers worldwide

Ten most important publications to date (reverse order)

Azimifar SB, Nagaraj N, Cox J, Mann M. Cell-type-resolved quantitative proteomics of murine 
liver. Cell Metab. 2014 Dec 2;20(6):1076-87 
 Scheltema RA, Hauschild JP, Lange O, Hornburg D, Denisov E, Damoc E, Kuehn A, Makarov A, 
Mann M. The Q Exactive HF, a Benchtop Mass Spectrometer with a Pre-filter, 
High-performance Quadrupole and an Ultra-high-field Orbitrap Analyzer. Mol Cell Proteomics. 
2014 Dec;13(12):3698-708 
Kulak NA, Pichler G, Paron I, Nagaraj N, Mann M. Minimal, encapsulated proteomic-sample 
processing applied to copy-number estimation in eukaryotic cells. Nat Methods. 2014 
Mann M, Kulak NA, Nagaraj N, Cox J. The coming age of complete, accurate, and ubiquitous 
proteomes. Mol Cell. 2013 Feb 21;49(4):583-90 
Meissner F, Scheltema RA, Mollenkopf HJ, Mann M. Direct proteomic quantification of the 
secretome of activated immune cells. Science. 2013 Apr 26;340(6131):475-8 
Cox J, Mann M. Quantitative, high-resolution proteomics for data-driven systems biology. 
Annu Rev Biochem. 2011 Jun 7;80:273-99 
Waanders LF, Chwalek K, Monetti M, Kumar C, Lammert E, Mann M. Quantitative proteomic 
analysis of single pancreatic islets. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):18902-7 
Cox J, Mann M. MaxQuant enables high peptide identification rates, individualized 
p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol. 2008 
Adachi, J., C. Kumar, Y. Zhang, J. V. Olsen and M. Mann . "The human urinary proteome 
contains more than 1500 proteins including a large proportion of membranes proteins." 2006 
Genome Biol 7(9): R80 
Aebersold, R. and M. Mann. "Mass spectrometry-based proteomics." Nature. 2003 
422(6928): 198-207